Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | SELL | P14151 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207808 | 0.89 | HTR1F (0.42) | PTPN5KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7213100 | 0.82 | KDM4E (0.57) | KDM4EMEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL7213112 | 0.82 | ANO1 (0.47) | KDM4EMEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL7213103 | 0.76 | KDM4E (0.41) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7214330 | 0.72 | KDM4E (0.56) | PPARGKDM4EMEN1KMT2ACYP2C9 | |
| SCHEMBL6000250 | 0.72 | PPARA (0.44) | PPARAPPARGKDM4EKMT2AALDH1A1 | |
| SCHEMBL7208144 | 0.69 | KDM4E (0.41) | PPARGKDM4EMEN1KMT2ACYP2C9 | |
| SCHEMBL7696769 | 0.68 | AKR1C2 (0.67) | KDM4EMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL7279576 | 0.68 | MAPK1 (0.62) | PPARAPPARGKMT2AALDH1A1GAA | |
| SCHEMBL8587020 | 0.67 | AKR1C2 (0.61) | PTPN5KDM4EMEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003508382-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1212296-A1 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | Sugen, Inc. (US) | 2002-06-12 | — | — | EP | claimed |
| WO-2001016097-A1 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN, INC. (US) | 2001-03-08 | — | — | WO | claimed |