Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206054 | 1.00 | GNAI3 (0.51) | GNAI3GNAO1GNAI1ANPEPERAP2 | |
| SCHEMBL12952257 | 0.93 | GNAI3 (0.42) | GNAI3GNAO1GNAI1ANPEPERAP2 | |
| SCHEMBL11801411 | 0.93 | ANPEP (0.53) | GNAI3GNAO1GNAI1ANPEPERAP2 | |
| SCHEMBL11791450 | 0.93 | ANPEP (0.53) | GNAI3GNAO1GNAI1ANPEPERAP2 | |
| SCHEMBL10998568 | 0.91 | PLA2G1B (0.46) | GNAI3GNAO1GNAI1ANPEPERAP2 | |
| SCHEMBL10974610 | 0.91 | PLA2G1B (0.46) | GNAI3GNAO1GNAI1ANPEPERAP2 | |
| SCHEMBL7081815 | 0.91 | PLA2G1B (0.46) | GNAI3GNAO1GNAI1ANPEPERAP2 | |
| SCHEMBL114607 | 0.91 | CA12 (0.48) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| SCHEMBL351230 | 0.91 | CA12 (0.48) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| SCHEMBL174695 | 0.91 | CA12 (0.48) | GNAI3GNAO1GNAI1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912584-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003519-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |
| EP-0308893-B1 | Process for producing dioctamethylene triamine | MITSUBISHI GAS CHEMICAL CO (JP) | 1994-01-05 | — | — | EP | disclosed |
| EP-0308894-B1 | PROCESS FOR PRODUCING DIOCTAMETHYLENE TRIAMINE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-12-11 | — | — | EP | disclosed |