SCHEMBL7208486

SCHEMBL7208486

O=C(O)c1cccnc1N1C=NCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.52
MYC P01106 1/20 0.51
KDM4E B2RXH2 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
BLM P54132 1/20 0.45
AGER Q15109 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
NAPRT Q6XQN6 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44
DHODH Q02127 4/20 0.42
MEN1 O00255 2/20 0.39
POLB P06746 1/20 0.39
RBP4 P02753 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8441014 0.76 ALDH1A1 (0.47) KMT2AMYCKDM4ETDP1L3MBTL1
SCHEMBL9247305 0.76 MYC (0.51) KMT2AMYCKDM4ETDP1L3MBTL1
SCHEMBL30106584 0.76 KMT2A (0.52) KMT2AMYCKDM4ETDP1L3MBTL1
SCHEMBL30477850 0.74 KMT2A (0.70) KMT2AMYCKDM4ETDP1L3MBTL1
SCHEMBL3309889 0.74 KMT2A (0.70) KMT2AMYCKDM4ETDP1L3MBTL1
SCHEMBL15294735 0.74 KMT2A (0.70) KMT2AMYCKDM4ETDP1L3MBTL1
SCHEMBL11399275 0.73 KMT2A (0.68) KMT2AMYCKDM4ETDP1L3MBTL1
SCHEMBL17746092 0.73 KMT2A (0.68) KMT2AMYCKDM4ETDP1L3MBTL1
SCHEMBL31057148 0.73 KMT2A (0.68) KMT2AMYCKDM4ETDP1L3MBTL1
SCHEMBL9245601 0.72 NPC1 (0.43) KMT2AKDM4ETDP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0163598-B1 HERBICIDAL COMPOSITIONS CIBA-GEIGY AG (CH) 1989-10-04 EP claimed
US-4822405-A AND 2,6-DINITROANILINE HERBICIDES AMERICAN CYANAMID COMPANY (US) 1989-04-18 US claimed
EP-1209970-B1 STABLE CONCENTRATED PESTICIDAL SUSPENSION MONSANTO TECHNOLOGY LLC (US) 2003-11-19 EP disclosed
US-6451731-B1 GLYPHOSATE HERBICIDE, IN SOLID PARTICULATE FORM, DISPERSED IN A LIQUID HERBICIDE SUCH AS ACETOCHLOR; NONAQUEOUS; SILICA SUSPENSION AID MONSANTO COMPANY 2002-09-17 US disclosed
EP-1209970-A1 STABLE CONCENTRATED PESTICIDAL SUSPENSION Monsanto Technology LLC (US) 2002-06-05 EP disclosed
WO-2001017346-A1 STABLE CONCENTRATED PESTICIDAL SUSPENSION MONSANTO TECHNOLOGY LLC. (US) 2001-03-15 WO disclosed
EP-0503332-B1 Process for extracting pyridine and quinoline dicarboxylic acids from aqueous media AMERICAN CYANAMID CO (US) 1998-08-26 EP disclosed
US-5397766-A Postemergence AMERICAN CYANAMID COMPANY (US) 1995-03-14 US disclosed
US-5268352-A N-phosphonomethylglycine AMERICAN CYANAMID COMPANY (US) 1993-12-07 US disclosed
US-5206368-A PROCESS FOR EXTRACTING PYRIDINE- AND QUINOLINEDICARBOXYLIC ACIDS FROM AQUEOUS MEDIA AMERICAN CYANAMID COMPANY (US) 1993-04-27 US disclosed
EP-0503332-A1 Process for extracting pyridine and quinoline dicarboxylic acids from aqueous media AMERICAN CYANAMID COMPANY (US) 1992-09-16 EP disclosed
EP-0277661-B1 IMIDAZOPYRROLOPYRIDINES AND CONDENSED DERIVATIVES THEREOF USEFUL IN THE PREPARATION OF HERBICIDAL COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1992-09-16 EP disclosed
EP-0433577-A1 Herbicidal emulsifiable suspension concentrate compositions AMERICAN CYANAMID COMPANY (US) 1991-06-26 EP disclosed
EP-0133309-B1 HERBICIDES AND METHOD FOR THE PREPARATION THEREOF AMERICAN CYANAMID COMPANY (US) 1989-11-23 EP disclosed
EP-0133310-B1 IMIDAZOLIDINONES, AND IMIDAZOLIDINETHIONES, PROCESS FOR THE PREPARATION THEREOF, AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS AMERICAN CYANAMID COMPANY (US) 1988-09-14 EP disclosed
EP-0277661-A1 Imidazopyrrolopyridines and condensed derivatives thereof useful in the preparation of herbicidal compounds AMERICAN CYANAMID COMPANY (US) 1988-08-10 EP disclosed
US-4701208-A Dihydroimidazopyrrolopyridine, quinoline, thieno- and furo[2,3-b]pyridine, dihydrothieno- and furo[2,3-b]-pyridine, thieno- and furo[3,2-b]pyridine and dihydrothieno- and furo[3,2-b]pyridine herbicides and method for preparation thereof AMERICAN CYANAMID COMPANY (US) 1987-10-20 US disclosed
US-4608079-A Imidazolidinones, and imidazolidinethiones, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1986-08-26 US disclosed
EP-0133310-A1 Imidazolidinones, and imidazolidinethiones, process for the preparation thereof, and use of said compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1985-02-20 EP disclosed