SCHEMBL7208490

SCHEMBL7208490

O=C(O)c1cnccc1C1=NCCN1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 14/20 0.46
KDM4C Q9H3R0 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
KDM6B O15054 1/20 0.41
KDM4A O75164 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4D Q6B0I6 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1526540 0.81 NISCH (0.60) NISCH
SCHEMBL30863845 0.77 KDM4C (0.57) KDM4CKDM4EMEN1KDM6BKDM4A
SCHEMBL12226606 0.77 NISCH (0.52) NISCH
SCHEMBL8376036 0.75 KDM4C (0.41) KDM4CKDM4EMEN1KDM6BKDM4A
SCHEMBL9675597 0.73 NISCH (0.60) NISCH
SCHEMBL7488646 0.72 NISCH (0.56) NISCHKDM4EALDH1A1
SCHEMBL9287530 0.72 NISCH (0.39) NISCHKDM4EALDH1A1TDP1
SCHEMBL7486584 0.71 NISCH (0.50) NISCHKDM4EALDH1A1L3MBTL1
SCHEMBL11716150 0.71 NISCH (0.55) NISCH
SCHEMBL30292662 0.71 ALDH1A1 (0.50) KDM4CKDM4EMEN1KDM6BKDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0163598-B1 HERBICIDAL COMPOSITIONS CIBA-GEIGY AG (CH) 1989-10-04 EP claimed
EP-1209970-B1 STABLE CONCENTRATED PESTICIDAL SUSPENSION MONSANTO TECHNOLOGY LLC (US) 2003-11-19 EP disclosed
US-6451731-B1 GLYPHOSATE HERBICIDE, IN SOLID PARTICULATE FORM, DISPERSED IN A LIQUID HERBICIDE SUCH AS ACETOCHLOR; NONAQUEOUS; SILICA SUSPENSION AID MONSANTO COMPANY 2002-09-17 US disclosed
EP-1209970-A1 STABLE CONCENTRATED PESTICIDAL SUSPENSION Monsanto Technology LLC (US) 2002-06-05 EP disclosed
WO-2001017346-A1 STABLE CONCENTRATED PESTICIDAL SUSPENSION MONSANTO TECHNOLOGY LLC. (US) 2001-03-15 WO disclosed
EP-0503332-B1 Process for extracting pyridine and quinoline dicarboxylic acids from aqueous media AMERICAN CYANAMID CO (US) 1998-08-26 EP disclosed
EP-0539676-B1 Oxime derivatives of formylpyridyl imidazolinones, the herbicidal us and methods for the preparation thereof AMERICAN CYANAMID CO (US) 1995-07-12 EP disclosed
US-5397766-A Postemergence AMERICAN CYANAMID COMPANY (US) 1995-03-14 US disclosed
US-5268352-A N-phosphonomethylglycine AMERICAN CYANAMID COMPANY (US) 1993-12-07 US disclosed
US-5225564-A Acetalization, amination or sulfiding in a solvent AMERICAN CYANAMID COMPANY (US) 1993-07-06 US disclosed
US-5215568-A OXIME DERIVATIVES OF FORMYLPYRIDYL IMIDAZOLINONES, THE HERBICIDAL USE AND METHODS FOR THE PREPARATION THEREOF AMERICAN CYANAMID COMPANY (US) 1993-06-01 US disclosed
EP-0539676-A1 Oxime derivatives of formylpyridyl imidazolinones, the herbicidal us and methods for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1993-05-05 EP disclosed
US-5206368-A PROCESS FOR EXTRACTING PYRIDINE- AND QUINOLINEDICARBOXYLIC ACIDS FROM AQUEOUS MEDIA AMERICAN CYANAMID COMPANY (US) 1993-04-27 US disclosed
EP-0503332-A1 Process for extracting pyridine and quinoline dicarboxylic acids from aqueous media AMERICAN CYANAMID COMPANY (US) 1992-09-16 EP disclosed
EP-0433577-A1 Herbicidal emulsifiable suspension concentrate compositions AMERICAN CYANAMID COMPANY (US) 1991-06-26 EP disclosed
US-4957536-A Method for increasing axillary branching, tillering, flowering and yield of agronomic and horticultural crops with certain 2-(2-imidazolin-2-yl)-pyridines and quinolines AMERICAN CYANAMID COMPANY (US) 1990-09-18 US disclosed
EP-0322616-A2 Novel 5(and/or 6)substituted 2-(2-imidazolin-2-yl)nicotinic acids, esters and salts, useful as herbicidal agents and nivel intermediates for the preparation of said nicotinic acids, esters and salts AMERICAN CYANAMID COMPANY (US) 1989-07-05 EP disclosed