Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209468 | 0.94 | TLR7 (0.48) | TLR7TSHRKDM4EALDH1A1GLA | |
| SCHEMBL7205381 | 0.89 | TLR7 (0.43) | TLR7TSHRKDM4EALDH1A1GAA | |
| SCHEMBL7209290 | 0.89 | TLR7 (0.40) | TLR7TSHRKDM4EALDH1A1GLA | |
| SCHEMBL7205100 | 0.89 | TLR7 (0.46) | TLR7TSHRKDM4EALDH1A1GLA | |
| SCHEMBL7211816 | 0.88 | TLR7 (0.44) | TLR7TSHRKDM4EALDH1A1GAA | |
| SCHEMBL7206075 | 0.88 | TLR7 (0.42) | TLR7TSHRKDM4EALDH1A1GAA | |
| SCHEMBL7210239 | 0.88 | ABCB1 (0.50) | TSHRALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL5464911 | 0.88 | TLR7 (0.41) | TLR7TSHRKDM4EALDH1A1GLA | |
| SCHEMBL7211524 | 0.87 | MAPK1 (0.45) | TLR7TSHRKDM4EALDH1A1GLA | |
| SCHEMBL7211567 | 0.87 | TSHR (0.44) | TLR7TSHRKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |