Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208552 | 0.94 | TLR7 (0.49) | TLR7KDM4EALDH1A1GLAGAA | |
| SCHEMBL7206075 | 0.92 | TLR7 (0.42) | TLR7KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7211524 | 0.90 | MAPK1 (0.45) | TLR7KDM4EALDH1A1GLAGAA | |
| SCHEMBL7205381 | 0.90 | TLR7 (0.43) | TLR7KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7205100 | 0.85 | TLR7 (0.46) | TLR7KDM4EALDH1A1GLAGAA | |
| SCHEMBL7211816 | 0.84 | TLR7 (0.44) | TLR7KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7210587 | 0.84 | TLR7 (0.44) | TLR7KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7210239 | 0.84 | ABCB1 (0.50) | ALDH1A1GAAMAPTTSHRMAPK1 | |
| SCHEMBL7209290 | 0.84 | TLR7 (0.40) | TLR7KDM4EALDH1A1GLAGAA | |
| SCHEMBL2060221 | 0.83 | ALDH1A1 (0.50) | TLR7KDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |