Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SELP | P16109 | 1/20 | 0.49 |
| ▸ | SELE | P16581 | 1/20 | 0.49 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000260 | 0.93 | SELP (0.55) | KMT2AMEN1MAPTSELPSELE | |
| SCHEMBL6001755 | 0.93 | KCNJ5 (0.51) | KMT2AMEN1MAPTKCNJ6KCNJ5 | |
| SCHEMBL6000277 | 0.89 | KCNJ5 (0.55) | KMT2AMEN1MAPTKCNJ6KCNJ5 | |
| SCHEMBL6001977 | 0.89 | KMT2A (0.57) | KMT2AMEN1MAPTSELPSELE | |
| SCHEMBL6001954 | 0.88 | LMNA (0.53) | KMT2AMEN1MAPTSELPSELE | |
| SCHEMBL6001780 | 0.83 | LMNA (0.57) | KMT2AMEN1MAPTKCNJ6KCNJ5 | |
| SCHEMBL6001084 | 0.78 | PRMT1 (0.57) | KMT2AMEN1MAPTEPHX2PRMT1 | |
| SCHEMBL6001655 | 0.75 | CA1 (0.57) | KMT2AMEN1KCNJ5KCNJ3PRMT1 | |
| SCHEMBL13764399 | 0.71 | CA1 (0.72) | KMT2AMEN1MAPTL3MBTL1EPHX2 | |
| SCHEMBL31654068 | 0.71 | RXFP1 (0.62) | KMT2AMEN1RXFP1P2RX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003508382-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1212296-A1 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | Sugen, Inc. (US) | 2002-06-12 | — | — | EP | claimed |
| WO-2001016097-A1 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN, INC. (US) | 2001-03-08 | — | — | WO | claimed |