Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 9/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208952 | 1.00 | LSS (0.44) | LSSL3MBTL1PDK2MCHR1THRA | |
| SCHEMBL7209249 | 0.91 | LSS (0.45) | LSSL3MBTL1MCHR1THRATHRB | |
| SCHEMBL7212794 | 0.91 | LSS (0.45) | LSSL3MBTL1PDK2MCHR1THRA | |
| SCHEMBL7212791 | 0.91 | LSS (0.45) | LSSL3MBTL1PDK2MCHR1THRA | |
| SCHEMBL7209246 | 0.91 | LSS (0.45) | LSSL3MBTL1MCHR1THRATHRB | |
| SCHEMBL7212170 | 0.90 | LSS (0.48) | LSSMCHR1THRATHRB | |
| SCHEMBL7204624 | 0.90 | LSS (0.56) | LSSMCHR1THRATHRB | |
| SCHEMBL7204630 | 0.90 | LSS (0.56) | LSSMCHR1THRATHRB | |
| SCHEMBL7204881 | 0.90 | LSS (0.56) | LSSMCHR1THRATHRB | |
| SCHEMBL7204876 | 0.90 | LSS (0.56) | LSSMCHR1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |