Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 15/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212167 | 1.00 | LSS (0.48) | LSSMCHR1THRATHRBMMP1 | |
| SCHEMBL7212794 | 0.91 | LSS (0.45) | LSSMCHR1THRATHRB | |
| SCHEMBL7212791 | 0.91 | LSS (0.45) | LSSMCHR1THRATHRB | |
| SCHEMBL7209246 | 0.91 | LSS (0.45) | LSSMCHR1THRATHRB | |
| SCHEMBL7209249 | 0.91 | LSS (0.45) | LSSMCHR1THRATHRB | |
| SCHEMBL7208948 | 0.90 | LSS (0.44) | LSSMCHR1THRATHRB | |
| SCHEMBL7208952 | 0.90 | LSS (0.44) | LSSMCHR1THRATHRB | |
| SCHEMBL7204876 | 0.90 | LSS (0.56) | LSSMCHR1THRATHRB | |
| SCHEMBL7204624 | 0.90 | LSS (0.56) | LSSMCHR1THRATHRB | |
| SCHEMBL7204881 | 0.90 | LSS (0.56) | LSSMCHR1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |