Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | F10 | P00742 | 11/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CALML3 | P27482 | 1/20 | 0.44 |
| ▸ | SDHA | P31040 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163888 | 1.00 | MAOA (0.48) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL6163251 | 1.00 | MAOA (0.48) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL7846895 | 0.91 | MAOA (0.54) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL6164089 | 0.91 | MAOA (0.54) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL6160348 | 0.91 | MAOA (0.54) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL7832146 | 0.91 | MAOA (0.54) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL8108944 | 0.89 | MAOA (0.51) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL6160328 | 0.89 | MAOA (0.61) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL7195331 | 0.89 | MAOA (0.61) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL6160326 | 0.89 | MAOA (0.61) | MAOAMAOBF10LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274426-A2 | USE OF THIOAMIDE OXAZOLIDINONES FOR THE TREATMENT OF BONE RESORPTION AND OSTEOPOROSIS | PHARMACIA & UPJOHN COMPANY (US) | 2003-01-15 | — | — | EP | claimed |
| WO-2001080841-A2 | USE OF THIOAMIDE OXAZOLIDINONES FOR THE TREATMENT OF BONE RESORPTION AND OSTEOPOROSIS | PHARMACIA & UPJOHN COMPANY (US) | 2001-11-01 | — | — | WO | claimed |