Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29487587 | 0.85 | SUV39H2 (0.44) | SUV39H2TSHRSMN1; SMN2TACR1ALDH1A1 | |
| SCHEMBL6433025 | 0.84 | SUV39H2 (0.37) | SUV39H2F2RL3ALDH1A1TBK1KDM4E | |
| SCHEMBL24460955 | 0.82 | BRD4 (0.40) | MAPT | |
| SCHEMBL18640108 | 0.76 | BTK (0.35) | SUV39H2SMN1; SMN2BTKALDH1A1TBK1 | |
| SCHEMBL22857365 | 0.74 | SUV39H2 (0.42) | SUV39H2TSHRSMN1; SMN2TACR1TBK1 | |
| SCHEMBL20010988 | 0.74 | SUV39H2 (0.40) | SUV39H2SMN1; SMN2BTKALDH1A1TBK1 | |
| SCHEMBL630016 | 0.73 | BTK (0.42) | SUV39H2BTKTBK1 | |
| SCHEMBL20010782 | 0.73 | MAPK14 (0.33) | SUV39H2BTKALDH1A1TBK1KDM4E | |
| SCHEMBL32662334 | 0.72 | SLC6A3 (0.41) | TSHRBTKALDH1A1KDM4E | |
| SCHEMBL634057 | 0.72 | SUV39H2 (0.40) | SUV39H2BTKTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318974-A2 | RESORCINOL DERIVATIVES | Pfizer Products Inc. (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024613-A2 | RESORCINOL DERIVATIVES | PFIZER PRODUCTS, INC. (US) | 2002-03-28 | — | — | WO | disclosed |
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | disclosed |