SCHEMBL7209213

SCHEMBL7209213

CCCCCCCCCCCCOCCCO[C]=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.48
THRB P10828 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48
MAPT P10636 1/20 0.48
CES2 O00748 2/20 0.45
ALDH1A1 P00352 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
USP2 O75604 1/20 0.38
TSHR P16473 2/20 0.38
CA1 P00915 6/20 0.38
CA2 P00918 6/20 0.38
CA9 Q16790 6/20 0.38
LPAR3 Q9UBY5 3/20 0.38
LPAR1 Q92633 2/20 0.38
LPAR2 Q9HBW0 2/20 0.38
CA12 O43570 2/20 0.38
CA3 P07451 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7252397 0.93 MEN1 (0.45) MEN1THRBHTTKMT2AMAPT
SCHEMBL7249899 0.93 MEN1 (0.45) MEN1THRBHTTKMT2AMAPT
SCHEMBL6759184 0.91 MEN1 (0.54) MEN1THRBHTTKMT2AMAPT
SCHEMBL8362606 0.91 MEN1 (0.54) MEN1THRBHTTKMT2AMAPT
SCHEMBL5482902 0.91 MEN1 (0.54) MEN1THRBHTTKMT2AMAPT
SCHEMBL5544295 0.91 MEN1 (0.54) MEN1THRBHTTKMT2AMAPT
SCHEMBL7254369 0.91 TSHR (0.46) MEN1THRBHTTKMT2AMAPT
SCHEMBL7248312 0.91 TSHR (0.46) MEN1THRBHTTKMT2AMAPT
SCHEMBL157306 0.91 CA1 (0.43) MEN1THRBHTTKMT2ACES2
SCHEMBL2858733 0.91 CA1 (0.43) MEN1THRBHTTKMT2ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903350-B1 Pyrrolotriazole derivative FUJI PHOTO FILM CO LTD (JP) 2003-03-12 EP disclosed
EP-0518238-B1 Pyrrolotriazole derivative FUJI PHOTO FILM CO LTD (JP) 1999-04-07 EP disclosed
EP-0903350-A1 Pyrrolotriazole derivative FUJI PHOTO FILM CO., LTD. (JP) 1999-03-24 EP disclosed
EP-0436938-B1 Silver halide color photographic material containing yellow colored cyan coupler FUJI PHOTO FILM CO LTD (JP) 1996-06-19 EP disclosed
US-5508421-A Pyrrolotriazole azomethine dye, and heat transfer dye providing material containing a pyrrolotriazole azomethine dye FUJI PHOTO FILM CO., LTD. (JP) 1996-04-16 US disclosed
EP-0451526-B1 Silver halide colour photographic materials FUJI PHOTO FILM CO LTD (JP) 1996-01-24 EP disclosed
US-5362882-A Intermediates for dyes for polyesters, images for heat sensitive elements and electrography FUJI PHOTO FILM CO., LTD. (JP) 1994-11-08 US disclosed
EP-0518238-A1 Pyrrolotriazole derivative FUJI PHOTO FILM CO., LTD. (JP) 1992-12-16 EP disclosed
EP-0451526-A2 Silver halide colour photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1991-10-16 EP disclosed
EP-0436938-A2 Silver halide color photographic material containing yellow colored cyan coupler Fuji Photo Film Co., Ltd. (JP) 1991-07-17 EP disclosed
US-4927743-A Silver halide photographic light-sensitive materials having specified coupler, dir coupler and silver coverage FUJI PHOTO FILM CO., LTD. (JP) 1990-05-22 US disclosed