Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 3/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788018 | 0.88 | GRIA4 (0.60) | GRIA4CTSLCTSBCTSSCTSK | |
| SCHEMBL6783719 | 0.85 | GRIA4 (0.63) | GRIA4CTSLCTSBCTSSCTSK | |
| SCHEMBL4584209 | 0.85 | GRIA4 (0.63) | GRIA4CTSLCTSBCTSSCTSK | |
| SCHEMBL6784440 | 0.85 | GRIA4 (0.56) | GRIA4CTSLCTSBCTSSCTSK | |
| SCHEMBL6790065 | 0.84 | GRIA4 (0.61) | GRIA4CTSLCTSBCTSSCTSK | |
| SCHEMBL6787350 | 0.83 | GRIA4 (0.64) | GRIA4CTSLCTSBCTSSCTSK | |
| SCHEMBL6789814 | 0.83 | GRIA4 (0.60) | GRIA4CTSLCTSBCTSSCTSK | |
| SCHEMBL6784120 | 0.83 | GRIA4 (0.54) | GRIA4CTSLCTSBCTSSCTSK | |
| SCHEMBL6787007 | 0.82 | EPHX1 (0.53) | GRIA4ALDH1A1OPRM1OPRD1 | |
| SCHEMBL6793790 | 0.82 | GRIA4 (0.53) | GRIA4CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617351-B1 | Amide, carbamate, and urea derivatives | ELI LILLY AND COMPANY | 2003-09-09 | — | — | US | disclosed |