Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.53 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788684 | 0.84 | GRIA4 (0.53) | GRIA4SMN1; SMN2HPGDSLC6A2SLC6A4 | |
| SCHEMBL6783128 | 0.83 | GRIA4 (0.54) | GRIA4SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7209225 | 0.82 | GRIA4 (0.59) | GRIA4ALDH1A1OPRM1OPRD1 | |
| SCHEMBL6788687 | 0.82 | GRIA4 (0.55) | GRIA4CYP2D6LMNA | |
| SCHEMBL6788018 | 0.81 | GRIA4 (0.60) | GRIA4ALDH1A1OPRM1OPRD1 | |
| SCHEMBL6783132 | 0.81 | GRIA4 (0.56) | GRIA4SMN1; SMN2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL6788859 | 0.81 | GRIA4 (0.54) | GRIA4SMN1; SMN2ALDH1A1HPGDSLC6A2 | |
| SCHEMBL6789642 | 0.80 | GRIA4 (0.56) | GRIA4SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6788862 | 0.78 | GRIA4 (0.56) | GRIA4LMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4584209 | 0.78 | GRIA4 (0.63) | GRIA4CYP2C19ALDH1A1CYP2D6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097499-A1 | Amide, carbamate, and urea derivatives | ARNOLD MACKLIN BRIAN (US) | 2004-05-20 | — | — | US | disclosed |
| EP-0976744-A1 | Amide, carbamate, and urea derivatives having glutamate receptor function potentiating activity | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097499-A1 | Amide, carbamate, and urea derivatives | GRIN2A, GLUL, GRIK5 | EPHX1 3444/4885GRIA4 16/4885SMN1; SMN2 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.