Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 19/20 | 0.71 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209347 | 1.00 | IMPDH2 (0.71) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL1477832 | 0.84 | IMPDH2 (0.72) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL1477829 | 0.84 | IMPDH2 (0.72) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL16504314 | 0.79 | IMPDH2 (0.65) | IMPDH2AAK1 | |
| SCHEMBL16504313 | 0.79 | IMPDH2 (0.65) | IMPDH2AAK1 | |
| SCHEMBL16504388 | 0.76 | IMPDH2 (0.51) | IMPDH2AAK1 | |
| SCHEMBL7210073 | 0.76 | IMPDH2 (0.60) | IMPDH2 | |
| SCHEMBL16504387 | 0.76 | IMPDH2 (0.51) | IMPDH2AAK1 | |
| SCHEMBL7210074 | 0.76 | IMPDH2 (0.60) | IMPDH2 | |
| SCHEMBL7210072 | 0.76 | IMPDH2 (0.60) | IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617323-B2 | For therapy and prophylaxis of transplant rejection and autoimmune diseases | BRISTOL-MYERS SQUIBB CO. | 2003-09-09 | — | — | US | disclosed |
| US-20020183315-A1 | Amino-substituted compounds useful as inhibitors of impdh enzyme | IWANOWICZ EDWIN J (US) | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183315-A1 | Amino-substituted compounds useful as inhibitors of impdh enzyme | IMPDH1, IMPDH2, ALDH7A1 | IMPDH2 2/4885AAK1 3168/4885IMPDH1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.