Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210660 | 0.90 | KDM4E (0.40) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7208930 | 0.89 | MEN1 (0.41) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4804845 | 0.81 | MEN1 (0.42) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL4804850 | 0.81 | MEN1 (0.42) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7208957 | 0.81 | EPHX2 (0.42) | — | |
| SCHEMBL4806203 | 0.79 | MAPK1 (0.44) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4806206 | 0.79 | MAPK1 (0.44) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7204545 | 0.79 | EPHX2 (0.40) | RECQLMAPK1 | |
| SCHEMBL7211914 | 0.78 | KDM4E (0.41) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7206295 | 0.77 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |