Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14983805 | 0.86 | TLR7 (0.46) | TLR7ADORA2AADORA1ADORA2BTLR8 | |
| SCHEMBL14983804 | 0.86 | TLR7 (0.48) | TLR7ADORA2AADORA1ADORA2BTLR8 | |
| SCHEMBL7209547 | 0.86 | TLR7 (0.46) | TLR7ADORA2AADORA1ADORA2BTLR8 | |
| SCHEMBL2060076 | 0.85 | TLR7 (0.46) | TLR7ADORA2AADORA1ADORA2BTLR8 | |
| SCHEMBL1001748 | 0.85 | TLR7 (0.64) | TLR7ADORA2AADORA1ADORA2B | |
| SCHEMBL5731164 | 0.84 | TLR7 (0.55) | TLR7ADORA2AADORA1ADORA2B | |
| SCHEMBL10174942 | 0.84 | TLR7 (0.49) | TLR7ADORA2AADORA1 | |
| SCHEMBL5732120 | 0.84 | TLR7 (0.63) | TLR7ADORA2AADORA1ADORA2B | |
| SCHEMBL2060517 | 0.83 | TLR7 (0.45) | TLR7ADORA2AADORA1ADORA2BTLR8 | |
| SCHEMBL5731379 | 0.83 | TLR7 (0.45) | TLR7ADORA2AADORA1ADORA2BTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |