Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.67 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.59 |
| ▸ | KDM4A | O75164 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.53 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.53 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13887195 | 1.00 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL17373920 | 1.00 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7208668 | 1.00 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7215984 | 1.00 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL12863577 | 1.00 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7203302 | 1.00 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7215946 | 1.00 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7208464 | 1.00 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL8995394 | 1.00 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| Hydrochloric Acid SCHEMBL17373841 | 0.98 | SLC6A5 (0.68) | SLC6A5PAOXKDM4AHIF1ATET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920434-A3 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F.HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | disclosed |
| EP-0920434-B1 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | HOFFMANN LA ROCHE (CH) | 2002-10-16 | — | — | EP | disclosed |
| US-6060616-A | ANTITUMORS AGENTS; LEUKEMIA, OVARIAN CARCINOMA | HOFFMANN-LA ROCHE INC. (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0920434-A2 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F.HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998003518-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |