SCHEMBL7209851

SCHEMBL7209851

COCCOc1nc(N)c2nc(Br)n(C(F)c3ccccc3)c2n1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.51
NUDT1 P36639 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3925877 0.79 TLR7 (0.43) TLR7NUDT1
SCHEMBL509587 0.77 TLR7 (0.74) TLR7NUDT1
SCHEMBL13728872 0.77 TLR7 (0.42) TLR7NUDT1
SCHEMBL4099733 0.77 TLR7 (0.42) TLR7NUDT1
SCHEMBL3925889 0.75 TLR7 (0.42) TLR7NUDT1
SCHEMBL4099745 0.74 TLR7 (0.40) TLR7NUDT1
SCHEMBL7209847 0.74 TLR7 (0.55) TLR7NUDT1
SCHEMBL14311956 0.73 TLR7 (0.51) TLR7NUDT1
SCHEMBL14303836 0.72 TLR7 (0.55) TLR7NUDT1
SCHEMBL4096425 0.72 TLR7 (0.46) TLR7NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1035123-B1 NOVEL HETEROCYCLIC COMPOUNDS SUMITOMO PHARMA (JP) 2003-08-20 EP disclosed
US-6329381-B1 INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2001-12-11 US disclosed
EP-1035123-A1 NOVEL HETEROCYCLIC COMPOUNDS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2000-09-13 EP disclosed