Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 13/20 | 0.39 |
| ▸ | CALML3 | P27482 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078331 | 0.92 | CALML3 (0.32) | MAOACALML3CYP2C19CYP2C9 | |
| SCHEMBL7081004 | 0.91 | CALML3 (0.42) | MAOACALML3CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL7081472 | 0.91 | MAOA (0.39) | MAOACALML3CYP2C19CYP2C9 | |
| SCHEMBL7081938 | 0.90 | CALML3 (0.41) | MAOACALML3CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL7077029 | 0.90 | CALML3 (0.41) | MAOACALML3CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL7079278 | 0.90 | MAOA (0.41) | MAOACALML3CYP2C19CYP2C9 | |
| SCHEMBL7210335 | 0.88 | MAOA (0.40) | MAOACALML3CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL7082570 | 0.88 | MAOA (0.41) | MAOACALML3CYP2C19CYP3A4 | |
| SCHEMBL7077036 | 0.88 | MAOA (0.43) | MAOACALML3CYP2C19CYP3A4 | |
| SCHEMBL7076915 | 0.87 | CALML3 (0.43) | MAOACALML3CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617339-B1 | 5-Isoxazolyloxymethyl-3-((dihydroxypropanoyl)-4-tetrahydropyri dyl-3,5- difluorophenyl)oxazolidinone, or the phosphated derivative or its disodium salt; antibiotic with useful activity against Grampositive pathogens | SYNGENTA LIMITED (GB) | 2003-09-09 | — | — | US | disclosed |