Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311880 | 0.93 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL7211992 | 0.88 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL5309601 | 0.84 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL5310941 | 0.84 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL5314644 | 0.83 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL7211955 | 0.83 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL5309608 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5314063 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5311624 | 0.81 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL7215303 | 0.81 | PTGS2 (0.65) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1369415-A1 | Substituted pyrrolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2003-12-10 | — | — | EP | disclosed |
| US-5935990-A | PYRROLYL DERIVATIVES HAVING AT POSITION 1 OR 5 A PHENYL SUBSTITUTED WITH METHYLSULFONYL OR AMINOSULFONYL; INHIBIT CYCLOOXYGENASE-2 FOR USE TREATMENT OF INFLAMMATION, AS AN ANALGESIC, OR AS AN ANTIPYRETIC | G.D. SEARLE & CO. (US) | 1999-08-10 | — | — | US | disclosed |