Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208083 | 0.94 | ELANE (0.68) | ELANE | |
| SCHEMBL7863330 | 0.84 | ELANE (0.70) | ELANE | |
| SCHEMBL6556446 | 0.83 | ELANE (0.69) | ELANE | |
| SCHEMBL6557614 | 0.81 | ELANE (0.62) | ELANE | |
| SCHEMBL6556086 | 0.80 | ELANE (0.80) | ELANE | |
| SCHEMBL6558297 | 0.80 | ELANE (0.73) | ELANE | |
| SCHEMBL9584142 | 0.80 | ELANE (1.00) | ELANE | |
| SCHEMBL9584587 | 0.80 | ELANE (0.79) | ELANE | |
| SCHEMBL8762836 | 0.77 | ELANE (0.75) | ELANE | |
| SCHEMBL7296453 | 0.77 | ELANE (0.64) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752987-B1 | PYRIMIDINYL DERIVATIVES AS INTERLEUKIN INHIBITORS | VERTEX PHARMA (US) | 2003-11-12 | — | — | EP | claimed |