SCHEMBL7210367

SCHEMBL7210367

CO/N=C(\C(=O)OC)c1ccccc1/C=N\O

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.46
HPGD P15428 3/20 0.39
LMNA P02545 3/20 0.39
HTT P42858 1/20 0.39
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7210372 1.00 HIF1A (0.46) HIF1AHPGDLMNAHTTUSP2
SCHEMBL7463069 1.00 HIF1A (0.46) HIF1AHPGDLMNAHTTUSP2
SCHEMBL7455959 0.87 HPGD (0.41) HIF1AHPGDLMNAHTTUSP2
SCHEMBL8761036 0.86 HPGD (0.38) HIF1AHPGDLMNAHTTUSP2
SCHEMBL7206001 0.85 HIF1A (0.48) HIF1ALMNAALDH1A1
SCHEMBL7209021 0.85 HIF1A (0.48) HIF1ALMNAALDH1A1
SCHEMBL8835428 0.85 HIF1A (0.48) HIF1ALMNAALDH1A1
SCHEMBL7211188 0.83 HIF1A (0.41) HIF1ALMNAGAA
SCHEMBL9236683 0.81 HIF1A (0.45) HIF1A
SCHEMBL8954615 0.80 HIF1A (0.47) HIF1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1076642-B1 PHENYL-METHOXYIMINO-GLYOXYLIC ACID DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-06-11 EP disclosed
US-6372787-B1 ESTER, OXIME DERIVATIVES FOR INSECTICIDES AND MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-04-16 US disclosed
EP-1076642-A1 PHENYL-METHOXYIMINO-GLYOXYLIC ACID DERIVATIVES AS PESTICIDES Novartis AG (CH) 2001-02-21 EP disclosed
WO-1999050232-A1 PHENYL-METHOXYIMINO-GLYOXYLIC ACID DERIVATIVES AS PESTICIDES NOVARTIS AG (CH) 1999-10-07 WO disclosed
EP-0738708-A1 Methoxyiminoacetic acid derivative and agricultural/horticultural fungicide containing the same as active ingredient Mitsubishi Chemical Corporation (JP) 1996-10-23 EP disclosed
US-5407902-A Methoxyiminoacetic acid derivative and agricultural/horticultural fungicide containing the same as active ingredient MITSUBISHI KASEI CORPORATION (JP) 1995-04-18 US disclosed
EP-0596254-A1 Methoxyiminoacetic acid derivative and agricultural/horticultural fungicide containing the same as active ingredient Mitsubishi Chemical Corporation (JP) 1994-05-11 EP disclosed