SCHEMBL7206001

SCHEMBL7206001

CON=C(C(=O)OC)c1ccccc1C=O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.48
MAPT P10636 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TLR2 O60603 1/20 0.36
ERN1 O75460 1/20 0.36
TLR1 Q15399 1/20 0.36
TLR6 Q9Y2C9 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8835428 1.00 HIF1A (0.48) HIF1AMAPTNPSR1MEN1LMNA
SCHEMBL7209021 1.00 HIF1A (0.48) HIF1AMAPTNPSR1MEN1LMNA
SCHEMBL9236683 0.87 HIF1A (0.45) HIF1A
SCHEMBL8460717 0.85 MAPT (0.48) HIF1AMAPTMEN1LMNAKMT2A
SCHEMBL9238440 0.85 HIF1A (0.44) HIF1A
SCHEMBL8460720 0.85 MAPT (0.48) HIF1AMAPTMEN1LMNAKMT2A
SCHEMBL7210367 0.85 HIF1A (0.46) HIF1ALMNAALDH1A1
SCHEMBL7463069 0.85 HIF1A (0.46) HIF1ALMNAALDH1A1
SCHEMBL7210372 0.85 HIF1A (0.46) HIF1ALMNAALDH1A1
SCHEMBL8760899 0.85 HIF1A (0.36) HIF1AMAPTMEN1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1076642-B1 PHENYL-METHOXYIMINO-GLYOXYLIC ACID DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-06-11 EP disclosed
US-6372787-B1 ESTER, OXIME DERIVATIVES FOR INSECTICIDES AND MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-04-16 US disclosed
EP-1076642-A1 PHENYL-METHOXYIMINO-GLYOXYLIC ACID DERIVATIVES AS PESTICIDES Novartis AG (CH) 2001-02-21 EP disclosed
CN-1057995-C Substituted ortho-ethenylphenylacetic acid derivatives BSAF AG (DE) 2000-11-01 CN disclosed
EP-0738708-B1 Methoxyiminoacetic acid derivative and agricultural/horticultural fungicide containing the same as active ingredient MITSUBISHI CHEM CORP (JP) 2000-02-02 EP disclosed
WO-1999050232-A1 PHENYL-METHOXYIMINO-GLYOXYLIC ACID DERIVATIVES AS PESTICIDES NOVARTIS AG (CH) 1999-10-07 WO disclosed
EP-0684226-B1 Imino-substituted phenyl derivatives, their preparation and fungicides containing them BASF AG (DE) 1998-05-06 EP disclosed
US-5719171-A INSECTICIDES; MITICIDES; NEMATOCIDES; FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-02-17 US disclosed
US-5633268-A FUNGICIDES, INSECTICIDES, PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-05-27 US disclosed
US-5594020-A FUNGICIDE BASF AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
EP-0684226-A1 Imino-substituted phenyl derivatives, their preparation and fungicides containing them BASF Aktiengesellschaft (DE) 1995-11-29 EP disclosed
US-5407902-A Methoxyiminoacetic acid derivative and agricultural/horticultural fungicide containing the same as active ingredient MITSUBISHI KASEI CORPORATION (JP) 1995-04-18 US disclosed
US-5389619-A Fungicide, insecticide and miticide; phenylacetic acid derivatives BASF AKTIENGESELLSCHAFT (DE) 1995-02-14 US disclosed
EP-0621277-A2 Diarylderivatives and their use for the protection of plants BASF Aktiengesellschaft (DE) 1994-10-26 EP disclosed
EP-0596254-A1 Methoxyiminoacetic acid derivative and agricultural/horticultural fungicide containing the same as active ingredient Mitsubishi Chemical Corporation (JP) 1994-05-11 EP disclosed
EP-0393428-B1 Oxiran-phenylesters and fungicides containing these BASF AG (DE) 1993-10-27 EP disclosed
US-5254717-A Imino-substituted phenyl derivatives, the preparation thereof and fungicides containing these BASF AKTIENGESELLSCHAFT (DE) 1993-10-19 US disclosed
EP-0499823-A2 Imino-substituted phenyl derivatives, their preparation and fungicides containing them BASF Aktiengesellschaft (DE) 1992-08-26 EP disclosed
US-5077303-A OXIRANE PHENYL ESTERS AND FUNGICIDES CONTAINING THESE BASF AKTIENGESELLSCHAFT (DE) 1991-12-31 US disclosed
EP-0393428-A1 Oxiran-phenylesters and fungicides containing these BASF Aktiengesellschaft (DE) 1990-10-24 EP disclosed