Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711246 | 0.91 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL7682625 | 0.90 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL7676356 | 0.90 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL7215484 | 0.89 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7676523 | 0.88 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL7680836 | 0.87 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL6710559 | 0.87 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL8525764 | 0.81 | PTGS2 (0.84) | PTGS2PTGS1 | |
| SCHEMBL7210588 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3824218 | 0.80 | PTGS2 (0.78) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117877625-A | Virtual screening method for inhibitor MPB with human cyclooxygenase 2 as target and inhibitor thereof | 重庆医科大学国际体外诊断研究院 | 2024-04-12 | — | — | CN | disclosed |
| EP-1369415-A1 | Substituted pyrrolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-0946507-A1 | SUBSTITUTED PYRROLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1999-10-06 | — | — | EP | disclosed |
| US-5935990-A | PYRROLYL DERIVATIVES HAVING AT POSITION 1 OR 5 A PHENYL SUBSTITUTED WITH METHYLSULFONYL OR AMINOSULFONYL; INHIBIT CYCLOOXYGENASE-2 FOR USE TREATMENT OF INFLAMMATION, AS AN ANALGESIC, OR AS AN ANTIPYRETIC | G.D. SEARLE & CO. (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1998025896-A1 | SUBSTITUTED PYRROLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-06-18 | — | — | WO | disclosed |