Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 9/20 | 0.47 |
| ▸ | CCR5 | P51681 | 8/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210650 | 1.00 | LSS (0.47) | LSSCCR5ELANEL3MBTL1 | |
| SCHEMBL4798935 | 0.93 | LSS (0.49) | LSSCCR5L3MBTL1 | |
| SCHEMBL4798925 | 0.93 | LSS (0.49) | LSSCCR5L3MBTL1 | |
| SCHEMBL4802753 | 0.93 | LSS (0.50) | LSSCCR5L3MBTL1 | |
| SCHEMBL4802760 | 0.93 | LSS (0.50) | LSSCCR5L3MBTL1 | |
| SCHEMBL4802988 | 0.91 | LSS (0.49) | LSSCCR5L3MBTL1 | |
| SCHEMBL4802996 | 0.91 | LSS (0.49) | LSSCCR5L3MBTL1 | |
| SCHEMBL4804179 | 0.89 | LSS (0.52) | LSSCCR5L3MBTL1 | |
| SCHEMBL4804176 | 0.89 | LSS (0.52) | LSSCCR5L3MBTL1 | |
| SCHEMBL7206156 | 0.89 | CCR5 (0.43) | LSSCCR5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |