Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | KDM5A | P29375 | 5/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210730 | 1.00 | EPHX2 (0.39) | EPHX2KDM5ALTA4HPOLBSMYD3 | |
| SCHEMBL4806637 | 0.88 | LSS (0.43) | EPHX2LTA4HPOLBLSS | |
| SCHEMBL4806631 | 0.88 | LSS (0.43) | EPHX2LTA4HPOLBLSS | |
| SCHEMBL7210724 | 0.80 | LTA4H (0.36) | EPHX2KDM5ALTA4HKDM4CKDM5C | |
| SCHEMBL7204545 | 0.79 | EPHX2 (0.40) | EPHX2KDM5ASMYD3KDM4CKDM5C | |
| SCHEMBL7206210 | 0.78 | MEN1 (0.39) | EPHX2KDM5ALTA4HKDM4CKDM5C | |
| SCHEMBL7210722 | 0.74 | KMT2A (0.38) | EPHX2KDM5ALTA4HPOLBKDM4C | |
| SCHEMBL7206207 | 0.74 | KDM5A (0.36) | EPHX2KDM5ALTA4HKDM4CKDM5C | |
| SCHEMBL7209339 | 0.73 | KDM5A (0.34) | EPHX2KDM5ALTA4HKDM4CKDM5C | |
| SCHEMBL7205082 | 0.73 | EPHX2 (0.42) | EPHX2KDM5AKDM4CKDM5CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |