Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1169040 | 0.82 | NPSR1 (0.30) | — | |
| SCHEMBL1168866 | 0.77 | CA2 (0.37) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL7212007 | 0.76 | CA2 (0.42) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL27330651 | 0.75 | CA2 (0.41) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL5505268 | 0.72 | CA2 (0.40) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL1169586 | 0.72 | CA2 (0.39) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL1168820 | 0.71 | CA2 (0.39) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL1168943 | 0.71 | CA2 (0.39) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL1169102 | 0.71 | CA2 (0.39) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL1168859 | 0.70 | CA2 (0.39) | CA2SMN1; SMN2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610734-B2 | For therapy of Alzheimer's Disease and Down's syndrome | WYETH | 2003-08-26 | — | — | US | disclosed |