Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628732 | 0.75 | HIF1A (0.43) | LMNASLC5A2HIF1APYGL | |
| SCHEMBL5574710 | 0.74 | PNP (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL4588335 | 0.74 | PNP (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL2778662 | 0.74 | PNP (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL5574698 | 0.74 | PNP (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL466334 | 0.74 | PNP (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL21206287 | 0.74 | DNMT1 (0.40) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL29122970 | 0.73 | PNP (0.46) | HIF1APYGL | |
| SCHEMBL5486410 | 0.73 | SLC5A2 (0.47) | SLC5A2HIF1APYGL | |
| SCHEMBL5483976 | 0.73 | SLC5A2 (0.47) | SLC5A2HIF1APYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617106-B1 | Methods for preparing oligonucleotides containing non-standard nucleotides | BENNER, STEVEN | 2003-09-09 | — | — | US | disclosed |
| US-6140496-A | Precursors for deoxyribonucleotides containing non-standard nucleosides | BENNER, STEVEN | 2000-10-31 | — | — | US | disclosed |
| US-6037120-A | PREPARATION OF A COMPLEMENTARY OLIGONUCLEOTIDE AND HYBRIDIZING TO DNA OR RNA IN SOLUTION | BENNER, STEVEN | 2000-03-14 | — | — | US | disclosed |
| US-6001983-A | Oligonucleotides with non-standard bases and methods for preparing same | BENNER, STEVEN | 1999-12-14 | — | — | US | disclosed |
| US-5432272-A | Genetic engineering | BENNER, STEVEN | 1995-07-11 | — | — | US | disclosed |