Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | MC4R | P32245 | 14/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210824 | 0.83 | KCNH2 (0.66) | KCNH2MC4R | |
| SCHEMBL4071377 | 0.79 | KCNH2 (1.00) | KCNH2MC4R | |
| SCHEMBL4816195 | 0.76 | KCNH2 (0.67) | KCNH2MC4R | |
| SCHEMBL4825430 | 0.76 | KCNH2 (0.76) | KCNH2MC4R | |
| SCHEMBL5793349 | 0.74 | KCNH2 (0.64) | KCNH2MC4R | |
| SCHEMBL4165894 | 0.74 | KCNH2 (0.89) | KCNH2MC4R | |
| Hydrochloric Acid SCHEMBL4911127 | 0.73 | KCNH2 (0.87) | KCNH2MC4R | |
| SCHEMBL4164988 | 0.70 | MC4R (0.62) | KCNH2MC4R | |
| SCHEMBL4822543 | 0.70 | KCNH2 (0.82) | KCNH2MC4R | |
| SCHEMBL4822793 | 0.70 | MC4R (0.67) | KCNH2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363890-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002062766-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-08-15 | — | — | WO | claimed |
| EP-1363890-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002062766-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-08-15 | — | — | WO | disclosed |