Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 6/20 | 0.69 |
| ▸ | PDE4A | P27815 | 1/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.69 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211003 | 1.00 | PDE4D (0.69) | PDE4DPDE4APDE4BPDE4CALDH1A1 | |
| Hydrochloric Acid SCHEMBL8387934 | 0.99 | PDE4D (0.68) | PDE4DPDE4APDE4BPDE4CALDH1A1 | |
| Hydrochloric Acid SCHEMBL8387939 | 0.99 | PDE4D (0.68) | PDE4DPDE4APDE4BPDE4CALDH1A1 | |
| Hydrochloric Acid SCHEMBL8390757 | 0.93 | PDE4D (0.58) | PDE4DPDE4APDE4BPDE4CALDH1A1 | |
| Hydrochloric Acid SCHEMBL7208480 | 0.93 | PDE4D (0.58) | PDE4DPDE4APDE4BPDE4CALDH1A1 | |
| Hydrochloric Acid SCHEMBL7207684 | 0.90 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4CALDH1A1 | |
| Hydrochloric Acid SCHEMBL7207679 | 0.90 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4CALDH1A1 | |
| SCHEMBL7209210 | 0.88 | PDE4D (0.75) | PDE4DPDE4APDE4BPDE4CALDH1A1 | |
| SCHEMBL13350269 | 0.88 | PDE4D (0.75) | PDE4DPDE4APDE4BPDE4CALDH1A1 | |
| SCHEMBL8327863 | 0.88 | PDE4D (0.75) | PDE4DPDE4APDE4BPDE4CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937074-B1 | BENZONAPHTHYRIDINES AS BRONCHIAL THERAPEUTICS | ALTANA PHARMA AG (DE) | 2003-03-12 | — | — | EP | disclosed |