Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211369 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL1804545 | 0.79 | KDM4E (0.63) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL22657901 | 0.79 | KDM4E (0.63) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL7279513 | 0.79 | KDM4E (0.63) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL7279508 | 0.79 | KDM4E (0.63) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL1804546 | 0.79 | KDM4E (0.63) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL29972290 | 0.78 | ALDH1A1 (0.50) | MAPTFOLH1MME | |
| SCHEMBL29596626 | 0.78 | KDM4E (0.58) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL7179431 | 0.75 | KDM4E (0.47) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL30539533 | 0.75 | KDM4E (0.47) | SMN1; SMN2KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370571-A2 | METHODS AND APPARATUS FOR GEL-FREE QUALITATIVE AND QUANTITATIVE PROTEOME ANALYSIS, AND USES THEREFOR | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. (BE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002077016-A2 | METHODS AND APPARATUS FOR GEL-FREE QUALITATIVE AND QUANTITATIVE PROTEOME ANALYSIS, AND USES THEREFORE | VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW (BE) | 2002-10-03 | — | — | WO | disclosed |