Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982532 | 0.98 | — | — | |
| SCHEMBL4286200 | 0.91 | — | — | |
| SCHEMBL29637725 | 0.79 | NOS2 (0.41) | NOS2EPHX1CES2CES1NPC1 | |
| SCHEMBL1260199 | 0.78 | — | — | |
| SCHEMBL6645101 | 0.76 | — | — | |
| SCHEMBL9303780 | 0.74 | — | — | |
| SCHEMBL15116589 | 0.74 | — | — | |
| SCHEMBL30075884 | 0.74 | NOS2 (0.38) | NOS2EPHX1CES2CES1NPC1 | |
| SCHEMBL30425687 | 0.73 | NOS2 (0.40) | NOS2 | |
| SCHEMBL7454047 | 0.73 | NOS2 (0.40) | NOS2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9078440-B2 | 6-(2-aminophenyl)picolinates and their use as herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-07-14 | — | — | US | claimed |
| US-4599416-A | Process for the preparation of aqueous solutions of potentiated sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 1986-07-08 | — | — | US | claimed |
| EP-2678349-B1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-01-13 | — | — | EP | disclosed |
| US-9139609-B2 | C-4″ position substituted macrolide derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-20140046043-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-02-13 | — | — | US | disclosed |
| EP-2678349-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-01-01 | — | — | EP | disclosed |
| WO-2012115256-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-08-30 | — | — | WO | disclosed |
| US-6616863-B1 | The enhanced electrical conductivity is isotropic as compared to a stretch oriental film which has isotropic electrical conductivity. | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-09-09 | — | — | US | disclosed |
| WO-2000006172-A1 | TREATMENT OF EQUINE PROTOZOAN MYELOENCEPHALITIS USING TRIAZINEDIONES | MORTAR & PESTLE VETERINARY PHARMACY, INC. (US) | 2000-02-10 | — | — | WO | disclosed |
| US-5830893-A | Treatment of equine protozoan myeloencephalitis using triazinediones | MORTAR & PESTLE VETERINARY PHARMACY, INC. (US) | 1998-11-03 | — | — | US | disclosed |
| US-4006163-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046043-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | MRPL21, MRPS34, MRPL37 | NOS2 4792/4885EPHX1 4578/4885ALOX5 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.