SCHEMBL7211588

SCHEMBL7211588

CCCCN=NC(C)(C#N)CC

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9067734 1.00 TSHR (0.30) TSHR
SCHEMBL8733561 0.83 TSHR (0.32) TSHR
SCHEMBL8733564 0.83 TSHR (0.32) TSHR
SCHEMBL10405949 0.82 TSHR (0.30) TSHR
SCHEMBL7206839 0.80 ALDH1A1 (0.30) TSHR
SCHEMBL10696900 0.79
SCHEMBL7119378 0.79
SCHEMBL14974 0.78 TSHR (0.32) TSHR
SCHEMBL26739217 0.78 TSHR (0.32) TSHR
SCHEMBL14973 0.78 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1307493-A2 POLYMERIC COMPOSITIONS FOR FORMING OPTICAL WAVEGUIDES; OPTICAL WAVEGUIDES FORMED THEREFROM; AND METHODS FOR MAKING SAME Goodrich Corporation (US) 2003-05-07 EP disclosed
WO-2002010231-A2 POLYMERIC COMPOSITIONS FOR FORMING OPTICAL WAVEGUIDES; OPTICAL WAVEGUIDES FORMED THEREFROM; AND METHODS FOR MAKING SAME GOODRICH CORPORATION (US) 2002-02-07 WO disclosed
US-5534174-A LUBRICANT ADDITIVE, DISPERSANT, VISCOSITY INDEX IMPROVER ETHYL PETROLEUM ADDITIVES, INC. (US) 1996-07-09 US disclosed
EP-0331323-B1 Demulsifier compositions and methods of preparation and use thereof PETROLITE CORP (US) 1994-08-24 EP disclosed
US-5260343-A Containing polyols, catalyst, chain extender, linear alcohol, surfactant, filler, pigments, antioxidants, stabilizers BASF CORPORATION (US) 1993-11-09 US disclosed
US-5102580-A Adding blend of block copolymer of oxyalkylated bishydroxyalkyl ether and cross-linked 2-amino-2-hydroxymethyl -1,3-propanediol in presence of mono or dialkyl sulfonic acid PETROLITE CORPORATION (US) 1992-04-07 US disclosed
US-4877842-A MODIFIED POLYOXYALKYLENE AMINE PETROLITE CORPORATION (US) 1989-10-31 US disclosed
EP-0331323-A2 Demulsifier compositions and methods of preparation and use thereof PETROLITE CORPORATION (US) 1989-09-06 EP disclosed
EP-0268713-A1 Demulsifier composition and method of use thereof PETROLITE CORPORATION (US) 1988-06-01 EP disclosed
EP-0257765-A1 Cold flow improver and method of use thereof PETROLITE CORPORATION (US) 1988-03-02 EP disclosed
US-4708993-A OLIGOMERS OF ESTER-CONTAINING HALOPOLYALKYENES AS OIL OR FUEL ADDITIVES PETROLITE CORPORATION (US) 1987-11-24 US disclosed
US-4626379-A REACTION PRODUCT OF BLEND OF POLYOXYALKYLENE OXIDE COPOLYMER AND VINYL MONOMER PETROLITE CORPORATION (US) 1986-12-02 US disclosed
US-4502977-A REACTION PRODUCT OF BLEND OF OXYALKYLATED MATERIALS WITH VINYL MONOMER PETROLITE CORPORATION (US) 1985-03-05 US disclosed