SCHEMBL7211908

SCHEMBL7211908

C#CCOC(=O)N(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24722063 0.80 NPC1 (0.37)
SCHEMBL28954012 0.79 NPC1 (0.36)
SCHEMBL10387999 0.77 TSHR (0.50)
SCHEMBL21445819 0.77 NPC1 (0.38)
SCHEMBL11008682 0.76
SCHEMBL21205900 0.76 NPC1 (0.37)
SCHEMBL25962131 0.76 CA12 (0.35)
SCHEMBL13034571 0.74 CHRNB2 (0.45)
SCHEMBL15800546 0.74 NPC1 (0.39)
SCHEMBL25962081 0.74 CA12 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0912557-B1 OXINDOLE DERIVATIVES ASTRAZENECA AB (SE) 2003-07-09 EP claimed
US-11958873-B2 Proteasome activity enhancing compounds Kineta, Inc. (US) 2024-04-16 US disclosed
US-20230299347-A1 Non-Aqueous Electrolyte Solution for Lithium Secondary Battery and Lithium Secondary Battery Comprising Same LG ENERGY SOLUTION, LTD. (KR) 2023-09-21 US disclosed
US-20230299347-A1 Non-Aqueous Electrolyte Solution for Lithium Secondary Battery and Lithium Secondary Battery Comprising Same LG ENERGY SOLUTION, LTD. (KR) 2023-09-21 US disclosed
US-20230242557-A9 PROTEASOME ACTIVITY ENHANCING COMPOUNDS Kineta, Inc. 2023-08-03 US disclosed
EP-4178002-A1 NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG Energy Solution, Ltd. (KR) 2023-05-10 EP disclosed
US-20220298181-A1 PROTEASOME ACTIVITY ENHANCING COMPOUNDS PROTEOSTASIS THERAPEUTICS INC (US) 2022-09-22 US disclosed
US-11242361-B2 Proteasome activity enhancing compounds PROTEOSTASIS THERAPEUTICS, INC. (US) 2022-02-08 US disclosed
EP-3518334-B1 NON-AQUEOUS ELECTROLYTE SOLUTION ADDITIVE, NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING SAID ADDITIVE LG CHEMICAL LTD (KR) 2021-04-21 EP disclosed
US-20200308198-A1 PROTEASOME ACTIVITY ENHANCING COMPOUNDS PROTEOSTASIS THERAPEUTICS, INC. 2020-10-01 US disclosed
EP-3518334-A1 NON-AQUEOUS ELECTROLYTE SOLUTION ADDITIVE, NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY, COMPRISING NON-AQUEOUS ELECTROLYTE SOLUTION ADDITIVE LG Chem, Ltd. (KR) 2019-07-31 EP disclosed
US-20180282352-A1 PROTEASOME ACTIVITY ENHANCING COMPOUNDS PROTEOSTASIS THERAPEUTICS, INC. 2018-10-04 US disclosed
US-9850262-B2 Proteasome activity enhancing compounds PROTEOSTASIS THERAPEUTICS, INC. (US) 2017-12-26 US disclosed
US-20160333031-A1 PROTEASOME ACTIVITY ENHANCING COMPOUNDS PROTEOSTASIS THERAPEUTICS, INC. 2016-11-17 US disclosed
WO-2015073528-A1 PROTEASOME ACTIVITY ENHANCING COMPOUNDS PROTEOSTASIS THERAPEUTICS, INC. (US) 2015-05-21 WO disclosed