Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27668498 | 0.87 | CYP1A2 (0.54) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL27668497 | 0.87 | CYP1A2 (0.54) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| Hydrochloric Acid SCHEMBL5553273 | 0.85 | MEN1 (0.55) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| Hydrochloric Acid SCHEMBL5553270 | 0.85 | MEN1 (0.55) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| Hydrochloric Acid SCHEMBL5662567 | 0.85 | MEN1 (0.55) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL7211938 | 0.84 | LMNA (0.54) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15087817 | 0.84 | MEN1 (0.58) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL19835585 | 0.84 | MEN1 (0.58) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL19836092 | 0.84 | MEN1 (0.58) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL10873632 | 0.83 | HTT (0.57) | CYP1A2TSHRNFKB1MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | disclosed |
| EP-0922050-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5750510-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997042205-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1997-11-13 | — | — | WO | disclosed |