Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466114 | 0.76 | SLC22A1 (0.36) | POLBKDM1A | |
| SCHEMBL7028452 | 0.74 | NPC1 (0.47) | MGLLPOLBKDM1AMAOAMAOB | |
| SCHEMBL5234339 | 0.73 | MGLL (0.46) | MGLLPOLBKDM1AMAOAMAOB | |
| SCHEMBL8503966 | 0.72 | POLB (0.67) | MGLLPOLB | |
| SCHEMBL7078296 | 0.72 | BTK (0.45) | MGLLPOLBNPC1ALDH1A1TP53 | |
| SCHEMBL5834261 | 0.71 | NAMPT (0.48) | MGLLPOLBMAOBALDH1A1MAPT | |
| SCHEMBL18786518 | 0.71 | MGLL (0.58) | MGLLPOLBKDM1AMAOAMAOB | |
| SCHEMBL7002216 | 0.70 | MGLL (0.42) | MGLLPOLBKDM1AMAOAMAOB | |
| SCHEMBL6608578 | 0.70 | MGLL (0.54) | MGLLPOLBNPC1ALDH1A1TP53 | |
| SCHEMBL8503162 | 0.70 | POLB (0.56) | MGLLPOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003515539-A | — | — | 2003-05-07 | — | — | JP | claimed |
| EP-1237895-A2 | PHOSPHORYLATION OF TERMINAL PRIMARY ALCOHOL GROUPS | AstraZeneca AB (SE) | 2002-09-11 | — | — | EP | claimed |
| WO-2001040236-A2 | PHOSPHORYLATION OF TERMINAL PRIMARY ALCOHOL GROUPS | ASTRAZENECA AB (SE) | 2001-06-07 | — | — | WO | claimed |
| EP-1237895-A2 | PHOSPHORYLATION OF TERMINAL PRIMARY ALCOHOL GROUPS | AstraZeneca AB (SE) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001040236-A2 | PHOSPHORYLATION OF TERMINAL PRIMARY ALCOHOL GROUPS | ASTRAZENECA AB (SE) | 2001-06-07 | — | — | WO | disclosed |