Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7217686 | 0.84 | SETD7 (0.58) | SETD7ALDH1A1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL9455483 | 0.82 | SETD7 (0.56) | SETD7ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9455598 | 0.82 | EBP (0.60) | SETD7ALDH1A1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL7217927 | 0.81 | EBP (0.58) | SETD7ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7213858 | 0.80 | SETD7 (0.56) | SETD7ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9455461 | 0.80 | SETD7 (0.53) | SETD7ALDH1A1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL7212338 | 0.79 | SETD7 (0.52) | SETD7ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7212631 | 0.78 | SETD7 (0.56) | SETD7ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9034573 | 0.78 | SIGMAR1 (0.56) | SETD7ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9034437 | 0.77 | SETD7 (0.54) | SETD7ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38257-E1 | Piperdine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 2003-09-23 | — | — | US | disclosed |
| US-5393890-A | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1995-02-28 | — | — | US | disclosed |
| US-5250681-A | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1993-10-05 | — | — | US | disclosed |