Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PPIB | P23284 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL654789 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7212914 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7206375 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7206378 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL12121841 | 0.78 | MAPT (0.50) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL654200 | 0.77 | MAPT (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7210858 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL10288244 | 0.72 | CCR1 (0.42) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7210855 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL4060672 | 0.68 | ALDH1A1 (0.66) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613905-B1 | Treating or preventing a disease associated with aberrant leukocyte recruitment and/or activation | MILLENNIUM PHARMACEUTICALS, INC. | 2003-09-02 | — | — | US | disclosed |