Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672787 | 0.82 | CREBBP (0.41) | CREBBPERCC5KDM4EALDH1A1MAPK1 | |
| SCHEMBL4671170 | 0.80 | CREBBP (0.47) | CREBBPERCC5KDM4EALDH1A1MAPK1 | |
| SCHEMBL4676341 | 0.79 | CREBBP (0.41) | CREBBPERCC5KDM4EALDH1A1MAPK1 | |
| SCHEMBL15155070 | 0.75 | ALKBH2 (0.55) | CREBBPERCC5KDM4EALDH1A1MAPK1 | |
| SCHEMBL27259480 | 0.72 | CREBBP (0.56) | CREBBPERCC5KDM4EALDH1A1MAPK1 | |
| SCHEMBL4674490 | 0.68 | KLKB1 (0.43) | CREBBPERCC5ALDH1A1L3MBTL1 | |
| SCHEMBL16827699 | 0.67 | CREBBP (0.51) | CREBBPKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL4672087 | 0.67 | KDM4C (0.39) | ERCC5KDM4EALDH1A1MAPK1MAPT | |
| SCHEMBL3470605 | 0.67 | ERCC5 (0.50) | CREBBPERCC5KDM4EALDH1A1MAPT | |
| SCHEMBL4678760 | 0.65 | KLKB1 (0.41) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620841-B1 | Furan or benzofuran derivatives substituted with triazole; acquired immunodeficiency syndrome (AIDS) | SHIONOGI & CO., LTD. (JP) | 2003-09-16 | — | — | US | disclosed |