Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | ADK | P55263 | 9/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115836 | 1.00 | HDAC6 (0.50) | HDAC6SLC15A1ADKCCNT1CDK9 | |
| SCHEMBL7742274 | 0.89 | HDAC6 (0.43) | HDAC6SLC15A1ADKCCNT1CDK9 | |
| SCHEMBL7742269 | 0.89 | HDAC6 (0.43) | HDAC6SLC15A1ADKCCNT1CDK9 | |
| SCHEMBL7124713 | 0.86 | HDAC6 (0.49) | HDAC6SLC15A1ADKCCNT1CDK9 | |
| SCHEMBL7739177 | 0.86 | HDAC6 (0.49) | HDAC6SLC15A1ADKCCNT1CDK9 | |
| SCHEMBL7739180 | 0.86 | HDAC6 (0.49) | HDAC6SLC15A1ADKCCNT1CDK9 | |
| SCHEMBL7739934 | 0.86 | HDAC6 (0.49) | HDAC6SLC15A1ADKCCNT1CDK9 | |
| SCHEMBL7739913 | 0.85 | SLC15A1 (0.38) | HDAC6SLC15A1ADKADORA3HSPA8 | |
| SCHEMBL7734303 | 0.85 | SLC15A1 (0.38) | HDAC6SLC15A1ADKADORA3HSPA8 | |
| SCHEMBL3925775 | 0.82 | HDAC6 (0.69) | HDAC6SLC15A1ADKHSPA8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617315-B1 | Sugar-substituted benzimidazole derivatives are used for the treatment or prophylaxis of restenosis, particularly following angioplasty | CHAMBERLAIN STANLEY DAWES (US) | 2003-09-09 | — | — | US | disclosed |
| US-6204249-B1 | L-benzimidazole nucleosides | GLAXO WELLCOME INC. | 2001-03-20 | — | — | US | disclosed |