SCHEMBL721325

SCHEMBL721325

CCCCc1ccc(C(=O)O)c(C(=O)O)c1CCCC(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.40
PPARA Q07869 4/20 0.39
BID P55957 3/20 0.39
MCL1 Q07820 3/20 0.39
BCL2L1 Q07817 2/20 0.39
BAK1 Q16611 2/20 0.39
KAT8 Q9H7Z6 2/20 0.39
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
GABRA2 P47869 2/20 0.39
GABRB2 P47870 2/20 0.39
GABRA4 P48169 2/20 0.39
GABRE P78334 2/20 0.39
GABRA6 Q16445 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL721324 1.00 METAP2 (0.40) METAP2PPARABIDMCL1BCL2L1
SCHEMBL722551 0.96 PPARA (0.44) PPARABIDMCL1BCL2L1BAK1
SCHEMBL722550 0.96 PPARA (0.44) PPARABIDMCL1BCL2L1BAK1
SCHEMBL5518812 0.96 BID (0.41) METAP2PPARABIDMCL1BCL2L1
SCHEMBL5180435 0.95 BID (0.43) METAP2PPARABIDMCL1BCL2L1
SCHEMBL5519803 0.95 BID (0.43) METAP2PPARABIDMCL1BCL2L1
SCHEMBL5519100 0.95 BID (0.43) METAP2PPARABIDMCL1BCL2L1
SCHEMBL5523259 0.95 BID (0.43) METAP2PPARABIDMCL1BCL2L1
SCHEMBL5516325 0.95 BID (0.43) METAP2PPARABIDMCL1BCL2L1
SCHEMBL5519682 0.95 BID (0.43) METAP2PPARABIDMCL1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1283222-B9 METHOD FOR PRODUCING A SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2019-11-13 EP disclosed
EP-1283222-B2 METHOD FOR PRODUCING A SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2019-03-27 EP disclosed
US-8648001-B2 Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same TOHO TITANIUM CO., LTD. (JP) 2014-02-11 US disclosed
EP-1283222-B1 SOLID CATALYST INGREDIENT AND CATALYST EACH FOR OLEFIN POLYMERIZATION AND PROPYLENE BLOCK COPOLYMER TOHO TITANIUM CO LTD (JP) 2012-07-04 EP disclosed
US-20120053310-A1 Aminosilane Compounds, Catalyst Components and Catalysts for Olefin Polymerization, and Process for Production of Olefin Polymers with the Same TOHO TITANIUM CO., LTD. (JP) 2012-03-01 US disclosed
US-7208435-B2 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2007-04-24 US disclosed
US-7141634-B2 Catalyst for olefin polymerization and process for polymerizing olefins TOHO CATALYST CO., LTD. (JP) 2006-11-28 US disclosed
US-20050054773-A1 Solid catalyst component for olefin polymerization, catalyst, and propylene block copolymer TOHO CATALYST CO, LTD. (JP) 2005-03-10 US disclosed
EP-1283222-A1 SOLID CATALYST INGREDIENT AND CATALYST EACH FOR OLEFIN POLYMERIZATION AND PROPYLENE BLOCK COPOLYMER Toho Catalyst Co., Ltd. (JP) 2003-02-12 EP disclosed