Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10527876 | 0.94 | RAB9A (0.61) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL23742932 | 0.94 | RAB9A (0.61) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL30105286 | 0.94 | RAB9A (0.61) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL16056268 | 0.92 | HPGD (0.68) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL6542880 | 0.89 | RAB9A (0.65) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL10575170 | 0.87 | RAB9A (0.57) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL7799815 | 0.84 | RAB9A (0.57) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL1238260 | 0.84 | RAB9A (0.57) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL7803998 | 0.83 | RAB9A (0.56) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL28986032 | 0.83 | RAB9A (0.74) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | disclosed |
| US-5750510-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |