Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.58 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743320 | 0.95 | GAA (0.51) | TP53TSHRPLA2G4BGAARAB9A | |
| Hydrochloric Acid SCHEMBL3743317 | 0.93 | PRSS1 (0.51) | TP53TSHRPLA2G4BGAARAB9A | |
| Hydrochloric Acid SCHEMBL9269065 | 0.92 | RARB (0.58) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL20333167 | 0.90 | PRMT1 (0.53) | TP53TSHRGAAPRMT1F2 | |
| SCHEMBL8994969 | 0.89 | PRMT1 (0.51) | TP53TSHRGAAPRMT1F2 | |
| SCHEMBL20333323 | 0.85 | PRMT1 (0.47) | TP53TSHRGAAPRMT1F2 | |
| SCHEMBL12461922 | 0.84 | PRSS1 (0.50) | GAARAB9APRMT1F2ST14 | |
| SCHEMBL8995027 | 0.82 | NPC1 (0.54) | TP53TSHRPLA2G4BNPC1LMNA | |
| SCHEMBL5219438 | 0.81 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 | |
| SCHEMBL9636880 | 0.81 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624309-B1 | Administering 4-heterocyclicbenzamide derivative | BRISTOL-MYERS SQUIBB COMPANY | 2003-09-23 | — | — | US | disclosed |
| US-20020137968-A1 | Benzoic acid derivatives and related compounds as antiarrhythmic agents | LLOYD JOHN (US) | 2002-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137968-A1 | Benzoic acid derivatives and related compounds as antiarrhythmic agents | SCN1A, SCN1B, NR0B1 | TP53 4875/4885TSHR 2565/4885PLA2G4B 3952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.