Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 7/20 | 0.56 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3838001 | 0.91 | AKT1 (0.53) | AKT1KDM1AMAOBMETAP2ADORA2A | |
| SCHEMBL3837608 | 0.87 | AKT1 (0.58) | AKT1KDM1AMAOBMETAP2PTGDR2 | |
| SCHEMBL1939360 | 0.87 | AKT1 (0.53) | AKT1KDM1AMAOBMETAP2PTGDR2 | |
| SCHEMBL30656042 | 0.82 | ADORA2A (0.50) | AKT1KDM1AMAOBADORA2AADORA1 | |
| SCHEMBL14430129 | 0.81 | KDM1A (0.54) | AKT1KDM1AMAOBMETAP2CYP11B2 | |
| SCHEMBL27452007 | 0.81 | CYP11B1 (0.42) | AKT1ADORA2AADORA1CYP11B1CYP11B2 | |
| SCHEMBL1940329 | 0.81 | PTGDR2 (0.49) | AKT1METAP2PTGDR2CYP19A1ADORA1 | |
| SCHEMBL5904305 | 0.79 | KDM1A (0.59) | AKT1KDM1AMAOBADORA1 | |
| SCHEMBL1939088 | 0.78 | AKT1 (0.64) | AKT1KDM1AMAOB | |
| SCHEMBL1652625 | 0.78 | AKT1 (0.66) | AKT1KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |