Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.40 |
| ▸ | F2 | P00734 | 6/20 | 0.40 |
| ▸ | PLG | P00747 | 5/20 | 0.40 |
| ▸ | PLAT | P00750 | 5/20 | 0.40 |
| ▸ | PROC | P04070 | 5/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.32 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456508 | 1.00 | F10 (0.40) | F10F2PLGPLATPROC | |
| SCHEMBL7456514 | 0.85 | F10 (0.38) | F10F2PLGPLATPROC | |
| SCHEMBL7213494 | 0.85 | F10 (0.38) | F10F2PLGPLATPROC | |
| SCHEMBL7214400 | 0.83 | F10 (0.40) | F10F2PLGPLATPROC | |
| SCHEMBL7448311 | 0.83 | F10 (0.40) | F10F2PLGPLATPROC | |
| Trifluoroacetic Acid SCHEMBL7219132 | 0.83 | KDR (0.35) | F10F2PLGPLATPROC | |
| Trifluoroacetic Acid SCHEMBL7219407 | 0.83 | KDR (0.35) | F10F2PLGPLATPROC | |
| Trifluoroacetic Acid SCHEMBL7446696 | 0.83 | KDR (0.35) | F10F2PLGPLATPROC | |
| Trifluoroacetic Acid SCHEMBL7219220 | 0.82 | F2 (0.34) | F10F2PLGPLATPROC | |
| Trifluoroacetic Acid SCHEMBL7213546 | 0.82 | F2 (0.34) | F10F2PLGPLATPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602864-B1 | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| EP-0944386-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | disclosed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |