SCHEMBL7213494

SCHEMBL7213494

N[C@H]1CCN(Cc2csc3ccnc(Cl)c23)C1=O

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 5/20 0.38
F2 P00734 3/20 0.38
PLG P00747 3/20 0.38
PROC P04070 3/20 0.38
PLAT P00750 2/20 0.38
IDH1 O75874 1/20 0.34
PRSS1 P07477 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7456514 1.00 F10 (0.38) F10F2PLGPROCPLAT
SCHEMBL7213490 0.85 F10 (0.40) F10F2PLGPROCPLAT
SCHEMBL7456508 0.85 F10 (0.40) F10F2PLGPROCPLAT
SCHEMBL7448318 0.82 F10 (0.38) F10F2PLGPROCPLAT
SCHEMBL7214401 0.82 F10 (0.38) F10F2PLGPROCPLAT
Trifluoroacetic Acid SCHEMBL7446703 0.80 KDR (0.36) F10F2PLGPROCPLAT
Trifluoroacetic Acid SCHEMBL7219133 0.80 KDR (0.36) F10F2PLGPROCPLAT
Trifluoroacetic Acid SCHEMBL7453206 0.79 HRH4 (0.34) F10F2PLGPROCPLAT
Trifluoroacetic Acid SCHEMBL7213548 0.79 HRH4 (0.34) F10F2PLGPROCPLAT
SCHEMBL7215808 0.75 F10 (0.47) F10F2PLGPROCPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6602864-B1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-08-05 US disclosed
EP-0944386-B1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMA INC (US) 2002-09-18 EP disclosed
US-6281227-B1 INHIBITORS OF THE ACTIVITY OF FACTOR XA. AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-08-28 US disclosed