Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369745 | 0.86 | ESR2 (0.38) | ESR2CYP3A4MEN1KMT2ATRPM8 | |
| Propionaldehyde SCHEMBL28691086 | 0.84 | ESR2 (0.37) | ESR2CYP3A4MEN1KMT2ATRPM8 | |
| SCHEMBL29364769 | 0.76 | CYP26B1 (0.37) | ESR2CYP2C9CYP2C19 | |
| SCHEMBL295952 | 0.76 | CYP26B1 (0.37) | ESR2CYP2C9CYP2C19 | |
| SCHEMBL27164761 | 0.75 | ESR2 (0.42) | ESR2TRPM8 | |
| SCHEMBL18741112 | 0.73 | ESR2 (0.41) | ESR2TRPM8 | |
| SCHEMBL27473293 | 0.71 | SLC6A2 (0.42) | KDM4ELMNATP53CYP3A4HIF1A | |
| SCHEMBL8795908 | 0.71 | CYP26B1 (0.51) | CYP3A4 | |
| SCHEMBL7143189 | 0.69 | CYP26B1 (0.47) | CYP3A4 | |
| SCHEMBL18741136 | 0.67 | TACR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150297482-A1 | MALODOR COUNTERACTING COMPOSITIONS AND METHOD FOR THEIR USE TO COUNTERACT SWEAT MALODOR | FIRMENICH SA (CH) | 2015-10-22 | — | — | US | disclosed |
| US-9101783-B2 | Malodor counteracting compositions and method for their use to counteract sweat malodor | FIRMENICH SA (CH) | 2015-08-11 | — | — | US | disclosed |
| US-20120052031-A1 | MALODOR COUNTERACTING COMPOSITIONS AND METHOD FOR THEIR USE TO COUNTERACT SWEAT MALODOR | FIRMENICH SA (CH) | 2012-03-01 | — | — | US | disclosed |