SCHEMBL295952

SCHEMBL295952

CC1(C)CCc2ccc(CCC=O)cc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP26B1 Q9NR63 2/20 0.37
CYP26A1 O43174 2/20 0.37
RXRA P19793 5/20 0.35
RXRB P28702 2/20 0.35
RXRG P48443 2/20 0.35
ESR1 P03372 3/20 0.33
ESR2 Q92731 3/20 0.33
RARA P10276 2/20 0.33
RARB P10826 1/20 0.33
RARG P13631 1/20 0.33
PLA2G4A P47712 1/20 0.33
TACR3 P29371 3/20 0.33
TACR1 P25103 2/20 0.33
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRM3 P20309 1/20 0.33
CHRNA4 P43681 1/20 0.33
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364769 1.00 CYP26B1 (0.37) CYP26B1CYP26A1RXRARXRBRXRG
SCHEMBL295214 0.89 ESR2 (0.38) CYP26B1CYP26A1RXRARXRBRXRG
SCHEMBL29369745 0.89 ESR2 (0.38) CYP26B1CYP26A1RXRARXRBRXRG
SCHEMBL18741136 0.87 TACR1 (0.32) CYP26B1CYP26A1TACR3TACR1
Propionaldehyde SCHEMBL28691086 0.85 ESR2 (0.37) CYP26B1CYP26A1RXRARXRBRXRG
SCHEMBL18740982 0.85 RARA (0.41) CYP26B1CYP26A1RXRARXRBRXRG
SCHEMBL8795908 0.84 CYP26B1 (0.51) CYP26B1CYP26A1RXRARXRBRXRG
SCHEMBL9770551 0.80 CNR1 (0.39) CYP26B1CYP26A1RXRARXRBRXRG
SCHEMBL11949124 0.79 KDM4E (0.40) CYP26B1CYP26A1RXRARXRBRXRG
SCHEMBL9770704 0.78 SKP2 (0.45) CYP26B1CYP26A1RXRAESR2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 470 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608360-A1 ANTI-DANDRUFF COMPOSITIONS Firmenich SA (CH) 2025-09-03 EP claimed
EP-4514477-A1 FRAGRANCE COMPOSITIONS HAVING LONG-LASTING TRAIL PERFORMANCE Firmenich SA (CH) 2025-03-05 EP claimed
EP-4438065-A2 A MIXTURE COMPRISING 1,2-ALKANEDIOLS Symrise AG (DE) 2024-10-02 EP claimed
EP-3251653-B1 MALODOR COUNTERACTING COMPOSITIONS AND METHOD FOR THEIR USE TO COUNTERACT SWEAT MALODOR FIRMENICH & CIE (CH) 2024-08-07 EP claimed
EP-4149913-B1 PROCESS FOR PREPARING INDENE ACRYLADEHYDE DERIVATIVES FIRMENICH & CIE (CH) 2024-07-17 EP claimed
WO-2024133645-A1 ANTI-DANDRUFF COMPOSITIONS FIRMENICH SA (CH) 2024-06-27 WO claimed
EP-3814469-B1 FABRIC TREATMENT COMPOSITIONS WITH POLYMER SYSTEM AND RELATED PROCESSES PROCTER & GAMBLE (US) 2024-01-17 EP claimed
WO-2023247599-A1 FRAGRANCE COMPOSITIONS HAVING LONG-LASTING TRAIL PERFORMANCE FIRMENICH SA (CH) 2023-12-28 WO claimed
US-20230271911-A1 PROCESS FOR PREPARING INDENE ACRYLADEHYDE DERIVATIVES FIRMENICH SA (CH) 2023-08-31 US claimed
CN-116568263-A Hair care composition comprising malodor reduction materials 宝洁公司 2023-08-08 CN claimed
EP-2655307-A1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS Givaudan SA (CH) 2013-10-30 EP claimed
CN-103261139-A Compounds capable of releasing fragrant compounds GIVAUDAN SA 2013-08-21 CN claimed
WO-2013045301-A1 FLORAL PERFUMING COMPOSITIONS AS SUBSTITUTES FOR LILIAL® FIRMENICH SA (CH) 2013-04-04 WO claimed
WO-2012085287-A1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS GIVAUDAN SA (CH) 2012-06-28 WO claimed
EP-2442782-A2 MALODOR COUNTERACTING COMPOSITIONS AND METHOD FOR THEIR USE TO COUNTERACT SWEAT MALODOR Firmenich S.A. (CH) 2012-04-25 EP claimed
US-20120052031-A1 MALODOR COUNTERACTING COMPOSITIONS AND METHOD FOR THEIR USE TO COUNTERACT SWEAT MALODOR FIRMENICH SA (CH) 2012-03-01 US claimed
WO-2010146556-A2 MALODOR COUNTERACTING COMPOSITIONS AND METHOD FOR THEIR USE TO COUNTERACT SWEAT MALODOR FIRMENICH SA (CH) 2010-12-23 WO claimed
EP-0685444-B1 Aromatic compounds and their use in perfumery FIRMENICH & CIE (CH) 2000-04-05 EP claimed
US-5552379-A FLORAL, FOR COSMETICS AND HOUSEHOLD ITEMS FIRMENICH SA (CH) 1996-09-03 US claimed
EP-0685444-A1 Aromatic compounds and their use in perfumery FIRMENICH SA (CH) 1995-12-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230271911-A1 PROCESS FOR PREPARING INDENE ACRYLADEHYDE DERIVATIVES HPD, IMPDH1, IMPDH2 CYP26B1 451/4885CYP26A1 1276/4885RXRA 4158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.