Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.76 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.76 |
| ▸ | ESR1 | P03372 | 7/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.55 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015672 | 0.88 | EBP (0.88) | EBPSIGMAR1ESR1ESR2HRH3 | |
| SCHEMBL113833 | 0.87 | EBP (0.73) | EBPSIGMAR1ESR1ESR2HRH3 | |
| Nafoxidine SCHEMBL29494604 | 0.86 | EBP (1.00) | EBPSIGMAR1ESR1ESR2HRH3 | |
| Nafoxidine SCHEMBL10563464 | 0.86 | EBP (1.00) | EBPSIGMAR1ESR1ESR2HRH3 | |
| Nafoxidine SCHEMBL153125 | 0.86 | EBP (1.00) | EBPSIGMAR1ESR1ESR2HRH3 | |
| Nafoxidine SCHEMBL115778 | 0.85 | EBP (0.98) | EBPSIGMAR1ESR1ESR2HRH3 | |
| Nafoxidine SCHEMBL29562423 | 0.85 | EBP (0.98) | EBPSIGMAR1ESR1ESR2HRH3 | |
| Nafoxidine SCHEMBL8430193 | 0.85 | EBP (0.98) | EBPSIGMAR1ESR1ESR2HRH3 | |
| SCHEMBL3804216 | 0.85 | EBP (0.82) | EBPSIGMAR1ESR1ESR2HRH3 | |
| SCHEMBL9993383 | 0.83 | EBP (0.74) | EBPSIGMAR1ESR1ESR2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608212-B1 | Palladium catalyzed coupling of a vinylphosphate and aryl-metal halide; preparation of such as 1-(4-(2-(pyrrolidin-n-yl)-ethoxy)phenyl)-6-methoxy-3,4-dihydronaphthalene | PFIZER, INC. | 2003-08-19 | — | — | US | disclosed |